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San Diego (59-95), which is trying to avoid its first 100-loss season in 15 years, scored five runs in the 14th inning on Friday to defeat Washington 11-6 in a painstaking five-hour game.
"They all end eventually," Padres manager Bud Black said. "It's not cricket."
Facing Levale Speigner - the ninth Washington pitcher - Chase Headley had an RBI triple, and scored on Nick Hundley's single. Brian Giles later drew a bases-loaded walk, and Adrian Gonzalez singled home two as the Padres won for the third time in four games against the Nationals this year.
Headley finished with four hits, and Gonzalez, Kevin Kouzmanoff and Will Venable added three each as San Diego totaled 20. Trevor Hoffman, the majors' all-time saves leader, appeared in his 900th game and retired the side in order to end the game.
Lastings Milledge had three hits, and Emilio Bonifacio drove in two for Washington (58-96), which hasn't lost 100 games since 1976 when the franchise was based in Montreal.
Washington manager Manny Acta said he doesn't want the distinction of having the NL's worst record.
"The only difference between 99 and 100 is two zeros," he said. "It's something you try to avoid, but if that's your goal, your goal is very low."
Chris Young (5-6, 4.43 ERA), who starts on Saturday for San Diego, has alternated wins and losses in three starts this month. Facing San Francisco last Saturday, the right-hander gave up three runs and seven hits with nine strikeouts through seven innings of the Padres' 7-0 loss.
Young had come within four outs of pitching a perfect game in his previous start against Milwaukee on Sept. 7. He hasn't faced the Nationals this season, and is 2-1 with a 3.32 ERA in three career starts against them.
Coming off his best start of the season for Washington, John Lannan (9-13, 3.97) will try to tie Tim Redding for the team lead in wins. The right-hander gave up one run and one hit with three walks and seven strikeouts over seven innings on Monday in a 7-2 win over the New York Mets.
Lannan told the Nationals' official Web site that he baffled Mets hitters with a lot of changeups.
"I felt more comfortable with it," he said. "I was more aggressive and I wasn't trying to do too much. ... I really relaxed and made sure I made my pitches."
Lannan did not get a decision in his only career start against the Padres. The Nationals lost 5-2 on May 29.
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